Sökresultat

We prospectively included 200 breast cancer patients assigned to neoadjuvant chemotherapy (NACT) in the NeoDense study (2014–2019). Raw data mammograms were used to assess MD with a fully automated volumetric method and radiologists categorized MD using the Breast Imaging-Reporting and Data System (BI-RADS), 5th Edition. Logistic regression was used to calculate odds ratios (OR) for pCR comparing

https://www.lupop.lu.se/article/mammographic-density-changes-during-neoadjuvant-breast-cancer-treatment-neodense-prospective-study - 2025-12-19

Conclusive evidence of superiority in oncological outcome for robot-assisted laparoscopic prostatectomy (RALP) over retropubic radical prostatectomy (RRP) is lacking. Read more at https://www.sciencedirect.com/science/article/pii/S2666168320351235

https://www.lupop.lu.se/article/risk-recurrent-disease-6-years-after-open-or-robotic-assisted-radical-prostatectomy-prospective - 2025-12-19

Aortic stenosis (AS) is the most common valvular heart disease in developed countries, confers high mortality in advanced cases, but can effectively be reversed using endovascular or open-heart surgery. We evaluated the association between AS and neighborhood socioeconomic status (NSES). Read more at https://www.sciencedirect.com/science/article/pii/S0167527320334124

https://www.lupop.lu.se/article/neighborhood-socioeconomic-status-and-aortic-stenosis-swedish-study-based-nationwide-registries-and - 2025-12-19

Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2–8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate the association

https://www.lupop.lu.se/article/polymorphism-killer-cell-immunoglobulin-receptors-and-human-leukocyte-antigen-c-and-predisposition - 2025-12-19

This paper examines social class differences in fertility, using longitudinal micro-level data for a regional sample in Sweden, 1922–2015. Using discrete-time event history models, we estimated the association between social class and parity-specific duration to next birth, adjusting for household income in separate models. Social class was associated with fertility quite independently from income

https://www.lupop.lu.se/article/social-class-and-fertility-long-run-analysis-southern-sweden-1922-2015-0 - 2025-12-19

In this cross-sectional study, a web-based survey was sent to 345 occupational therapists with less than 10 years of work experience, with 252 responding. Data was collected using the Swedish Demand-Control-Support Questionnaire and questions on job strain and sociodemographics. Read more at https://www.tandfonline.com/doi/full/10.1080/11038128.2020.1817544

https://www.lupop.lu.se/article/perceived-job-strain-among-swedish-occupational-therapists-less-10-years-work-experience - 2025-12-19

Hallux rigidus (HR), which affects approximately 2% of the population, can be graded based on the severity of the disease (Lucas et al. 2015, Lam et al. 2017, Galois et al. 2020). Beeson et al. (2008) conducted a literature review of the existing multiple classification systems where the system promoted by Coughlin and Shurnas (2003) was deemed to have the most reliable grading. Read more at https

https://www.lupop.lu.se/article/patient-reported-outcomes-joint-preserving-surgery-moderate-hallux-rigidus-1-year-follow-296 - 2025-12-19

The Swedish National Register for Esophageal and Gastric cancer was launched in 2006 and contains data with adequate national coverage and of high internal validity on patients diagnosed with these tumors. The aim of this study was to describe the evolution of esophageal and gastric cancer care as reflected in a population-based clinical registry. The study population was 12,242 patients (6,926 wi

https://www.lupop.lu.se/article/improvements-esophageal-and-gastric-cancer-care-sweden-population-based-results-2007-2016-national - 2025-12-19

Modern modular implants allow surgeons to mix different combinations of components within the same brand. From 1999 to 2012, the NexGen®-CR Option femoral component, together with a NexGen® Option Stemmed tibial plate (stemmed baseplate), which uses a short central stem, was the most-frequently used NexGen® combination in the Swedish Knee Arthroplasty Register. However, from 1999 to 2012, the same

https://www.lupop.lu.se/article/higher-risk-loosening-four-pegged-tka-tibial-baseplate-stemmed-one-register-based-study - 2025-12-19

Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. Read more at https://pubmed.ncbi.nlm.nih.g

https://www.lupop.lu.se/article/extrapancreatic-infections-are-common-acute-pancreatitis-and-they-are-related-organ-failure - 2025-12-19

To determine whether alcohol use disorder (AUD) is transmitted within families as predicted by contagion, we examined parent-offspring, siblings, and cousin pairs ascertained from Swedish registries with a primary case with AUD. Our outcome variable was AUD registration in at-risk secondary cases. In offspring, risks for AUD registration in the 3 years after a parental index registration residing

https://www.lupop.lu.se/article/within-family-transmission-alcohol-use-disorder-parent-offspring-sibling-and-cousin-pairs-contagion - 2025-12-19

Specific birth‐related fractures have been studied; underestimates might be a problem. We aimed to assess all fractures diagnosed as birth‐related as well as other neonatal fractures. Read more at https://onlinelibrary.wiley.com/doi/full/10.1111/apa.15217

https://www.lupop.lu.se/article/difficult-birth-main-contributor-birth-related-fracture-and-accidents-other-neonatal-fractures - 2025-12-19

Consecutively excised symptomatic foreskins from 351 men were sent for histopathological evaluation. During the surgical procedure, a fresh biopsy was taken for HPV analysis by modified general primer polymerase chain reaction. A medical questionnaire regarding medication, smoking habits, number of lifetime sexual partners, former diseases and surgery performed on penis was completed by all partic

https://www.lupop.lu.se/article/penile-intraepithelial-neoplasia-penile-cancer-precursors-and-human-papillomavirus-prevalence - 2025-12-19

To evaluate how surgeon heterogeneity – the variation in outcomes between individual surgeons – influences functional and oncological outcomes after robot‐assisted laparoscopic prostatectomy (RALP) and retropubic radical prostatectomy (RRP), and to assess whether surgeon heterogeneity affects the comparison between RALP and RRP. Read more at https://bjui-journals.onlinelibrary.wiley.com/doi/full/1

https://www.lupop.lu.se/article/surgeon-heterogeneity-significantly-affects-functional-and-oncological-outcomes-after-radical - 2025-12-19

This was a cross‐sectional study based on data from 1591 adults (16–76y, median age 25y; 879 males, 712 females; Communication Function Classification System [CFCS] levels I–V) in the Swedish Cerebral Palsy Follow‐up Program. Pain severity was rated for several body sites and pain interference with activities/work and sleep was also evaluated. Logistic regression was used to estimate the odds rati

https://www.lupop.lu.se/article/prevalence-pain-and-interference-daily-activities-and-sleep-adults-cerebral-palsy - 2025-12-19

Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential associations between DM, C

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden-0 - 2025-12-19

Social and biological circumstances at birth are established predictors of adult socioeconomic position (SEP). This study aims to assess the trends in these associations across two generations and examine the effects of parental early-life characteristics on descendants’ adult SEP. Read more at https://jech.bmj.com/content/jech/early/2020/01/27/jech-2019-213209.ful…

https://www.lupop.lu.se/article/early-life-social-and-health-determinants-adult-socioeconomic-position-associations-and-trends - 2025-12-19

Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adverse birth ou

https://www.lupop.lu.se/article/occupational-exposure-whole-body-vibrations-and-pregnancy-complications-nationwide-cohort-study - 2025-12-19

Swedish national breast cancer guidelines recommend that all women diagnosed with breast cancer (BC) at the age of 35 years or younger should be referred to their regional oncogenetic clinic for genetic counseling and testing, regardless of family history of cancer. The main objective of this study was to evaluate whether place of residence at BC diagnosis and treating hospital were associated wit

https://www.lupop.lu.se/article/variations-referral-pattern-genetic-counseling-patients-early-onset-breast-cancer-population-based - 2025-12-19

The rise in antibiotic resistance is a global public health concern, and antibiotic overuse needs to be reduced. Earlier studies of out-of-hours care have indicated that antibiotic prescribing is less appropriate than that of in-hours care. However, no study has compared the out-of-hours treatment of infections to in-hours treatment within the same population. Read more at https://bmcinfectdis.bio

https://www.lupop.lu.se/article/diagnosis-linked-antibiotic-prescribing-swedish-primary-care-comparison-between-hours-and-out-hours - 2025-12-19